This website provides specific details about the COMET Study, a clinical trial hosted by a national co-operative group - Alliance Foundation Trials, LLC - and funded by the Patient-Centered Outcomes Research Institute (PCORI). This study is registered with Clinicaltrials.gov.

The Principal Investigator (PI) of COMET is Dr. Shelley Hwang, Professor of Surgery and Chief of Breast Surgical Oncology at the Duke University Medical Center and Duke Cancer Institute. Co-PIs of the study are Dr. Alastair Thompson, Professor of Surgery and Chief of Breast Surgical Oncology at Baylor College of Medicine, and Dr. Ann Partridge, a Breast Medical Oncologist and Professor of Medicine at Harvard Medical School and Dana Farber Cancer Institute.

The members of the COMET Study Patient Leadership Team (PLT) are Elizabeth Frank; Deborah Collyar; Desiree Basila; and Donna Pinto. Members of the PLT possess vast DCIS experience and expertise including: engagement in breast cancer research for over 20 years; undergoing active monitoring for DCIS; publishing a DCIS e-book; developing a patient advocate research organization; and hosting a DCIS website.

The project manager of the COMET Study is Thomas Lynch, PhD, Senior Researcher in the Division of Surgical Oncology at Duke University Medical Center. The statistician for the COMET Study is Terry Hyslop, PhD, Professor of Biostatistics and Bioinformatics in the Division of Integrative Genomics at Duke University.

Study recruitment and implementation is being supported by consultants Dr. Louise Davies (Giesel School of Medicine at Dartmouth College), and Jenny Donovan, PhD, (University of Bristol, UK).

This work was supported through a Patient-Centered Outcomes Research Institute (PCORI) Award (PCS-1505-30497). All statements in this website are solely those of the authors and do not necessarily represent the views of PCORI, its Board of Governors or Methodology Committee.